Anti-Aging – Pentadecyl®

Pentadecyl® is a natural anti-aging cosmetic ingredient derived from the marine microalgae Aurantiochytrium, known for producing beneficial fatty acids such as DHA and EPA. The active consists primarily of odd-chain saturated fatty acids—especially pentadecanoic acid (C15)—extracted and purified from the microalga’s triglycerides.

Highly potent at just 1 ppm, Pentadecyl® significantly improves fine wrinkles around the eyes compared to placebo, with no reported adverse reactions. It strengthens the skin barrier by increasing Filaggrin expression, reduces trans-epidermal water loss (TEWL), and promotes Type I collagen production in dermal fibroblasts—supporting firmness, elasticity, and long-term skin health.

NAGASE supplies Pentadecyl® across EMEA markets with full technical support and global logistics capabilities.

Pentadecyl® is mainly used in advanced anti-aging and skin barrier–repair formulations.

• Anti-aging skincare – wrinkle-reducing creams and firming serums
• Moisturizing & barrier-repair products – reduces TEWL for improved hydration
• Barrier-strengthening creams – supports tight junction integrity (Claudin-1, Involucrin)
• Formulas for sensitive & dry skin – soothing, protective, and restorative care
• Post-treatment recovery care – supports regeneration after dermatological procedures
• Premium natural or marine-based cosmetic lines

Pentadecyl® offers a safe, natural, and marine-derived solution for visible wrinkle reduction and barrier enhancement.

• Improves fine wrinkles caused by dryness and aging
• Boosts hydration and barrier resilience by reducing TEWL
• Promotes collagen synthesis and enhances cellular activity
• Dual-action anti-aging benefits via structural and metabolic pathways
• Sustainable microalgae origin with excellent skin compatibility

What is Pentadecyl® used for in skincare?
Pentadecyl® is used in anti-aging, moisturizing, and barrier-repair formulations to improve wrinkles, enhance hydration, and strengthen the skin barrier.

How does Pentadecyl® reduce wrinkles?
Pentadecyl® contains microalgae-derived C15 fatty acids that increase collagen production and improve skin structure, leading to a visible reduction in fine wrinkles.

Is Pentadecyl® suitable for sensitive skin?
Yes, Pentadecyl® is gentle, well-tolerated, and helps soothe and protect sensitive or dry skin by reducing TEWL and supporting barrier proteins like Filaggrin.

How potent is Pentadecyl® in cosmetic formulations?
Pentadecyl® is highly effective at just 1 ppm and has shown clinically significant wrinkle improvements with no adverse reactions.

Is Pentadecyl® a natural ingredient?
Yes, Pentadecyl® is a natural, sustainable active sourced from marine microalgae, compliant for use in EMEA and China.